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Writer's pictureFreed From Evil

Magnetogenetics through Mrna technologies

Control of mouse behavior through Genetic manipulation is being done now. See detailed article here: Magnogenetics - A New Technique For Controlling Mouse Behavior.

For Bombshell article that exposes all this, see the article below:



Here's an excerpt:


A SINGLE IMMUNIZATION WITH SPIKE-FUNCTIONALIZED FERRITIN VACCINES ELICITS NEUTRALIZING ANTIBODY RESPONSES AGAINST SARS-COV-2 IN MICE

Cite this: ACS Cent. Sci. 2021, 7, 1, 183–199Publication Date: January 5, 2021 https://doi.org/10.1021/acscentsci.0c01405

Copyright © 2021 The Authors. Published by American Chemical Society

“The development of a safe and effective SARS-CoV-2 vaccine is a public health priority. We designed subunit vaccine candidates using self-assembling ferritin nanoparticles displaying one of two multimerized SARS-CoV-2 spikes: full-length ectodomain (S-Fer) or a C-terminal 70 amino-acid deletion (SΔC-Fer). Ferritin is an attractive nanoparticle platform for production of vaccines, and ferritin-based vaccines have been investigated in humans in two separate clinical trials. We confirmed proper folding and antigenicity of spike on the surface of ferritin by cryo-EM and binding to conformation-specific monoclonal antibodies. After a single immunization of mice with either of the two spike ferritin particles, a lentiviral SARS-CoV-2 pseudovirus assay revealed mean neutralizing antibody titers at least 2-fold greater than those in convalescent plasma from COVID-19 patients. Additionally, a single dose of SΔC-Fer elicited significantly higher neutralizing responses as compared to immunization with the spike receptor binding domain (RBD) monomer or spike ectodomain trimer alone. After a second dose, mice immunized with SΔC-Fer exhibited higher neutralizing titers than all other groups. Taken together, these results demonstrate that multivalent presentation of SARS-CoV-2 spike on ferritin can notably enhance elicitation of neutralizing antibodies, thus constituting a viable strategy for single-dose vaccination against COVID-19.”


THE STUDY IS FINANCED BY MARK AND PRISCILLA ZUCKERBERG THROUGH BIOHUB!


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